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American Society of Clinical Oncology (ASCO)
American Society of Clinical Oncology (ASCO)
The
American Society of Clinical Oncology
(
ASCO
) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide.
Efficacy of Amivantamab (JNJ-61186372) in Patients with NSCLC Harboring EGFR Exon 20 Insertion Mutation
ASCO 2020 – Wrap Up
Results from the CHRYSALIS study show that amivantamab demonstrates robust and durable antitumor activity and a manageable safety profile in patients with
EGFR
exon20ins-mutated non–small-cell lung cancer.
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Barriers to Targeted Therapies for NSCLC Patients with Highly Actionable Gene Variants in the Veterans Health Affairs Program
ASCO 2020 – Wrap Up
A substantial minority of patients with advanced non–small-cell lung cancer and highly actionable gene variants were not prescribed available targeted therapies in the Veterans Health Affairs National Precision Oncology Program.
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ADAURA Results: Osimertinib as Adjuvant Therapy for EGFR-Mutated NSCLC
ASCO 2020 – Lung Cancer
Approximately 30% of patients with non–small-cell lung cancer present with early-stage (I-IIIA) disease and undergo surgery. Researchers assessed the use of adjuvant osimertinib in this population.
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Patterns of Acquired Resistance in Patients with NSCLC Who Receive PD-1 Inhibitors
ASCO 2020 – Lung Cancer
The frequency and durability of outcomes associated with acquired resistance to PD-1 inhibition in non–small-cell lung cancer are presented.
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Characteristics of Patients Who Achieve Long-Term Response with PD-1 Blockade
ASCO 2020 – Lung Cancer
The characteristics of long-term responders to PD-1 blockade are presented.
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Smoking Cessation and Lung Cancer: Recent Quitters Benefit Too
ASCO 2020 – Lung Cancer
For oncologists and others who advocate for smoking cessation, it is important to know whether recent quitters who are diagnosed with lung cancer can achieve a survival benefit.
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Weekly Epirubicin as Second-Line Therapy for Malignant Pleural Mesothelioma
ASCO 2020 – Lung Cancer
Weekly epirubicin was evaluated as a potential “gentle” option for second-line chemotherapy in patients with malignant pleural mesothelioma after failure of first-line pemetrexed-based chemotherapy.
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Combination of Nivolumab, Ipilimumab, and Chemotherapy in Metastatic NSCLC
ASCO 2020 – Lung Cancer
Combining nivolumab plus ipilimumab with 2 cycles of chemotherapy may be effective in patients undergoing first-line treatment for metastatic non–small-cell lung cancer.
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Nationwide Genomic Screening Network Can Be Effective in Identifying Rare Targetable Genetic Alterations
ASCO 2020 – Lung Cancer
Developing novel targeted therapies for patients with cancer who have rare mutations, such as PI3K/AKT/mTOR pathway alterations, is particularly challenging for researchers.
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Cediranib Combined with Olaparib Is Active in Patients with Platinum-Pretreated SCLC
ASCO 2020 – Lung Cancer
Patients with platinum-pretreated small-cell lung cancer may benefit from combination use of cediranib, an oral VEGF inhibitor, and olaparib, a PARP inhibitor.
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