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American Society of Hematology (ASH)
ASH 2019 – Multiple Myeloma
ASH 2019 – Multiple Myeloma
In Relapsed or Refractory Myeloma, Addition of Elotuzumab to Lenalidomide + Dexamethasone Improves Outcomes with No Detriment to Quality of Life
ASH 2019 – Multiple Myeloma
Final analysis of patient-reported outcomes from the phase 3 ELOQUENT-2 trial confirms elotuzumab has no negative impact on health-related quality of life.
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Videos
Triplets versus Quads
By
Leslie Lauersdorf, ARNP
ASH 2019 – Multiple Myeloma
Leslie Lauersdorf explains triplet versus quad regimens in relation to multiple myeloma.
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Adding Elotuzumab to Pomalidomide, Bortezomib, and Dexamethasone Leads to Promising Responses in Relapsed/Refractory Multiple Myeloma
ASH 2019 – Multiple Myeloma
In patients with relapsed/refractory multiple myeloma, treatment with elotuzumab in combination with pomalidomide, bortezomib, and dexamethasone shows encouraging responses, with manageable toxicity.
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Videos
CAR T-Cell Data in Multiple Myeloma
By
Leslie Lauersdorf, ARNP
ASH 2019 – Multiple Myeloma
Leslie Lauersdorf discusses key considerations for nurses and navigators surrounding the use of CAR T-cell therapy in multiple myeloma.
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COLUMBA Update: Subcutaneous Daratumumab Shows Similar Efficacy to IV Formulation in Relapsed/Refractory Multiple Myeloma, with Fewer Adverse Events
ASH 2019 – Multiple Myeloma
Compared with intravenous (IV) administration, subcutaneous daratumumab led to similar response rates with fewer infusion-related reactions.
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Videos
Latest Developments in Multiple Myeloma
By
Leslie Lauersdorf, ARNP
ASH 2019 – Multiple Myeloma
Leslie Lauersdorf provides an overview of some of the most exciting clinical developments in multiple myeloma based on data presented at ASH 2019.
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Novel Myeloma Regimen Improves Outcomes in Systemic AL Amyloidosis
ASH 2019 – Multiple Myeloma
In systemic amyloid light chain (AL) amyloidosis, treatment with ixazomib/dexamethasone proved more beneficial than treatment of physician’s choice, although hematologic response was not improved.
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Selinexor + Pomalidomide + Dexamethasone Combination Leads to Promising Response Rates in Relapsed or Refractory Multiple Myeloma
ASH 2019 – Multiple Myeloma
Selinexor, pomalidomide, and dexamethasone led to high response rates in patients with multiple myeloma who were refractory to lenalidomide and had not been previously treated with pomalidomide.
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Daratumumab + Lenalidomide + Dexamethasone Combination Continues to Improve Progression-Free Survival in Relapsed or Refractory Multiple Myeloma
ASH 2019 – Multiple Myeloma
After more than 4 years of median follow-up, treatment with daratumumab, lenalidomide, and dexamethasone continues to improve progression-free survival compared with lenalidomide and dexamethasone alone in relapsed/refractory multiple myeloma, with deep and durable responses.
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Clinical Trial Discontinuation Significantly Lower in Patients Treated with Daratumumab
ASH 2019 – Multiple Myeloma
Despite safety concerns related to daratumumab, a meta-analysis of 5 large randomized controlled trials showed no significant increase in treatment delays, trial discontinuation, or treatment-related deaths in patients with untreated or relapsed/refractory multiple myeloma who received the drug.
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