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American Society of Hematology (ASH)
American Society of Hematology (ASH)
The
American Society of Hematology
(
ASH
) is a professional organization representing hematologists. It was founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes the medical journal
Blood
, the most cited peer-reviewed publication in the field, which is available weekly in print and online, as well as the newly launched, online, peer-reviewed open-access journal,
Blood Advances
.
Prognostic Biomarker Testing, Treatment Patterns, and Dosing Among Patients with CLL/SLL
ASH 2020 – CLL: Wrap-Up
The informCLL registry of adult patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) can help to resolve knowledge gaps that may be identified in the evaluation and treatment of patients with CLL/SLL.
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Venetoclax plus Decitabine versus Intensive Chemotherapy for Treating Relapsed/Refractory AML
ASH 2020 – AML
As salvage therapy in younger patients with relapsed/refractory acute myeloid leukemia (AML), the efficacy of 10-day decitabine + venetoclax is comparable to intensive chemotherapy regimens and is an appropriate bridge to allogeneic stem-cell transplantation.
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Ibrutinib plus Venetoclax for First-Line Treatment of CLL/SLL: Results from the CAPTIVATE Study
ASH 2020 – CLL: Wrap-Up
Primary results from the CAPTIVATE study demonstrate that fixed-duration treatment with ibrutinib plus venetoclax offers treatment-free remission for patients with previously untreated chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).
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FLAG-IDA Intensive Induction/Consolidation plus Venetoclax in Newly Diagnosed or R/R AML Patients
ASH 2020 – AML
Across multiple acute myeloid leukemia (AML) subgroups, venetoclax + FLAG-IDA was effective, elicited deep responses, and had an acceptable safety profile, representing an attractive option as a bridge to allo-SCT for adverse-risk, newly diagnosed, and relapsed/refractory (R/R) AML patients.
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Combination Ibrutinib plus Venetoclax for Relapsed/Refractory CLL: Long-Term Follow-Up Data
ASH 2020 – CLL: Wrap-Up
Combination ibrutinib plus venetoclax treatment results in sustained response in patients with relapsed or refractory chronic lymphocytic leukemia (CLL). This response is sustained despite planned discontinuation in patients who had achieved minimal residual disease.
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Selinexor plus 7+3 and HDAC Consolidation Is Highly Active in Older Adults with Newly Diagnosed Acute Myeloid Leukemia
ASH 2020 – AML
In older patients with de novo acute myeloid leukemia, the combination of selinexor with standard induction and consolidation therapy appears highly active.
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Clonal Dynamics After Venetoclax-Obinutuzumab Therapy in Patients with CLL
ASH 2020 – CLL: Wrap-Up
Individual clonal growth rates can be used to estimate the minimal residual disease doubling time after fixed-duration treatment. Clonal growth rates were lower after treatment with venetoclax-obinutuzumab when compared with chlorambucil-obinutuzumab.
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After No Response to Enasidenib, Adding Azacitidine Is Effective for Older Patients with IDH2-Mutated AML
ASH 2020 – AML
In patients with newly diagnosed
IDH2
mut
acute myeloid leukemia (AML), treatment with enasidenib was associated with low early death and high complete response and complete response with incomplete hematologic recovery rates and yielded durable remission.
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Idecabtagene Vicleucel, a BCMA-Directed CAR T-Cell Therapy, in Patients with RRMM: CRB-401 Study Updates
ASH 2020 – Multiple Myeloma
Updated analysis of the phase 1 CRB-401 study supports a favorable clinical benefit–risk profile for the BCMA-directed CAR T-cell therapy, idecabtagene vicleucel, in RRMM at target dose levels of ≥150 × 106 CAR+ T-cells.
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Thalidomide plus Prednisone and Methotrexate for Symptomatic Large Granular Lymphocytic Leukemia
ASH 2020 – CLL: Wrap-Up
The combination regimen of thalidomide, prednisone, and methotrexate demonstrated greater efficacy than treatment with cyclosporine and prednisone in patients with large granular lymphocytic leukemia and with limited adverse events.
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