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San Antonio Breast Cancer Symposium (SABCS)
SABCS 2022
SABCS 2022
HR-Positive/HER2-Negative Breast Cancer
Patient-Reported Outcomes and Progression-Free Survival Findings from the 5th Interim Analysis of the RIBANNA Trial in Patients with HR-Positive/HER2-Negative Advanced Breast Cancer
SABCS 2022
Interim analysis of the RIBANNA trial demonstrates that ribociclib provides a meaningful PFS benefit and maintains QOL in patients with HR-positive/HER2-negative advanced breast cancer.
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HR-Positive/HER2-Negative Breast Cancer
Pooled Analysis of Post-Progression Treatments after Ribociclib in the MONALEESA-2, -3, and -7 Trials in Patients with HR-Positive/HER2-Negative Advanced Breast Cancer
SABCS 2022
Post-progression targeted therapy after ribociclib found to result in increased duration of therapy.
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HR-Positive/HER2-Negative Breast Cancer
Ribociclib-Derived Resistance Mutations: ctDNA Findings from the MONALEESA-2, -3, and -7 Trials
SABCS 2022
Comprehensive analysis of acquired resistance mutations in patients with HR-positive/HER2-negative advanced breast cancer post-CDK4/6 inhibitor and endocrine therapy is the largest to date.
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HR-Positive/HER2-Negative Breast Cancer
Pooled Analysis of Gene Expression and Associated Treatment Response in the MONALEESA-2, -3, and -7 Trials
SABCS 2022
Results from the MONALEESA trials show that PFS benefit with ribociclib in combination with endocrine therapy found to be consistent regardless of expression levels of most cell cycle genes.
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HR-Positive/HER2-Negative Breast Cancer
Comparison of Progression-Free Survival from the MONALEESA and RIBANNA Trials in Patients with HR-Positive/HER2-Negative Advanced Breast Cancer
SABCS 2022
Analysis from the MONALEESA and RIBANNA trials in patients with HR-positive/HER2-negative advanced breast cancer finds differences in PFS among patients treated with ribociclib in combination with endocrine therapy among MONALEESA-like subgroups.
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