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HER2+ Breast Cancer and CDK4/6 Inhibitors
SABCS 2017
Dr Hope Rugo discusses studies that are aiming to evaluate the effect that CDK4/6 inhibitors have on patients with HER2+ breast cancer.
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Videos
Hot Topics at SABCS 2017
SABCS 2017
Dr Hope Rugo provides an overview of some hot topics being covered at SABCS 2017 in the areas of hormone therapy, immunotherapy, neoadjuvant therapy, and more.
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Videos
Abemaciclib, Ribociclib, or Palbociclib for HR+ Metastatic Breast Cancer?
SABCS 2017
Dr Matthew Goetz reviews what differentiates abemaciclib, the latest CDK4/6 inhibitor FDA-approved for HR+ metastatic breast cancer, from ribociclib and palbociclib.
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CDK4/6 Inhibitors vs Chemotherapy for Patients with Metastatic Breast Cancer
SABCS 2017
Despite international guidelines and data that show CDK4/6 inhibitors plus aromatase inhibitors can improve overall response rates, overall survival, and progression-free survival in patients with metastatic breast cancer, there is a lasting belief among patients that chemotherapy is the preferable course of treatment. Dr. Hope Rugo attempts to dispel this misconception, citing that endocrine therapy and CDK4/6 inhibitors are well tolerated and don’t have the intensive side effects associated with chemotherapy.
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Videos
CDK4/6 Inhibitors in HER2+ Metastatic Breast Cancer
SABCS 2017
Dr Matthew Goetz addresses the prospect of utilizing CDK4/6 inhibitors to treat patients with HER2+ metastatic breast cancer, stating early data indicate that CDK4/6 inhibitors may have some antitumor activity in HER2+ breast cancer.
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Videos
The Mechanism of Action of CDK4/6 Inhibitors
SABCS 2017
Dr Matthew Goetz explains the rationale for using CDK4/6 inhibitors in patients with HR-positive metastatic breast cancer.
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Videos
The Use of Chemotherapy in the Metastatic Setting
SABCS 2017
Dr Matthew Goetz believes that, as more mature data come into existence, the demonstration of a survival advantage will guide more patients with metastatic breast cancer to try CDK4/6 inhibitors plus aromatase inhibitors instead of chemotherapy.
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Videos
Questions About Treating Patients Using a CDK4/6 Inhibitor
SABCS 2017
Dr Matthew Goetz addresses common questions that arise when patients with HER+ metastatic breast cancer have progressed on a CDK4/6 inhibitor plus an aromatase inhibitor.
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Videos
A Look at SIRT Y-90 and the SARAH Trial
ILC 2017
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Videos
Tailoring Treatment
EHA 2016
Nikhil Munshi talks about modifying treatment to patients' expectations and what they can tolerate.
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